Costantini Lab

Biography

Dr. Costantini earned his MSc in Industrial Chemistry and his PhD in Chemical and Process Engineering from Sapienza University of Rome. He then pursued postdoctoral research at the Warsaw University of Technology, Università Campus Bio-Medico di Roma, and the Institute of Physical Chemistry of the Polish Academy of Sciences.

Since 2022, he is leading a multidisciplinary team at the same institute, operating at the interface of materials science, biology, and microfluidics. His research focuses on the development of digital manufacturing strategies for functionally graded porous materials with enhanced physicochemical properties, as well as on advanced methods for in vitro modeling and in vivo musculoskeletal regeneration.

Published with us

From Prediction to Design: A Machine Learning Tool for Porous Mechanical Metamaterials

Available at SSRN 5254863 •

Biography

Published with us

From Prediction to Design: A Machine Learning Tool for Porous Mechanical Metamaterials

Functionally Graded Spherical-Based Porous Architectures Via Low Force Stereolithography: In Silico Design and Experimental Validation

Microfluidic-mixer assisted 3D printing of functionally graded multimaterial hydrogels for engineering complex tissue interfaces

Spherical-based Mechanical Metamaterials: from Prediction to Design via Machine Learning

Enhancing Conductivity in 3D Organic Electrochemical Transistors with PEDOT–Tetramethacrylate Integration

Modular biofabrication of a vascularized skeletal muscle model through endothelialized microvascular seeds

Decoupling Shape Retention from Polymerization Kinetics Enables Ambient-Temperature 3D Printing of Polystyrene

Recapitulating the human myotendinous junction in vitro using a 3D bioprinted model

Methacrylated pulmonary dECM-enriched GelMA bioinks promote endothelialization and angiogenesis in 3D printed tubular constructs

3D bioprinting in tissue engineering: current state-of-the-art and challenges towards system standardization and clinical translation

3D Rotary Wet‐Spinning (RoWS) Biofabrication Directly Affects Proteomic Signature and Myogenic Maturation in Muscle Pericyte–Derived Human Myo‐Substitute

Mimicking the Dystrophic Cardiac Extracellular Environment through DystroGel

Microfluidic 3D bioprinting of foamed fibers with controlled micromorphology

Study of the interplay among melt morphology, rheology and 3D printability of poly (lactic acid)/poly (3-hydroxybutyrate-co-3-hydroxyvalerate) blends

Bioactive hydrogel supplemented with stromal cell-derived extracellular vesicles enhance wound healing

Modeling breast cancer dynamics through modulable small Vessel Environment Bioreactor (sVEB)

A machine learning-aided design framework for bone tissue engineering scaffolds

Microfluidic bubble‐generator enables digital light processing 3D printing of porous structures

Automated Microfluidics‐Assisted Hydrogel‐Based Wet‐Spinning for the Biofabrication of Biomimetic Engineered Myotendinous Junction

Tuna-step: tunable parallelized step emulsification for the generation of droplets with dynamic volume control to 3D print functionally graded porous materials

Engineering Biomimetic Microvascular Capillary Networks in Hydrogel Fibrous Scaffolds via Microfluidics-Assisted Co-Axial Wet-Spinning

Enhancing neovascularization post-myocardial infarction through injectable hydrogel functionalized with endothelial-derived EVs

Spherical-based porous architectures: In silico design and validation

Automated Microfluidics‐Assisted Hydrogel‐Based Wet‐Spinning for the Biofabrication of Biomimetic Engineered Myotendinous Junction (Adv. Healthcare Mater. 32/2024)

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In silico-aided design of functionally graded porous scaffolds for bone tissue engineering

3D Bioprinting in Microgravity

Microfluidic-assisted co-axial wet-spinning extrusion of microvascularized hydrogel fibers with low viscous bioinks

Microfluidic-assisted spinning for engineering skeletal muscle and skeletal muscle interfaces

Microfluidic 3D biofabrication for the patterning of hierarchical gradient constructs

A validation method of the FE model for the design of bone tissue engineering scaffolds

Biofabricated wet-spun core-shell hydrogel fibers for microvascular tissue engineering

Chitosan and its derivatives in 3D/4D (bio) printing for tissue engineering and drug delivery applications

3D bioprinting in microgravity: opportunities, challenges, and possible applications in space

In vitro functional models for human liver diseases and drug screening: beyond animal testing

Microfluidic 3D printing of emulsion ink for engineering porous functionally graded materials

Combining rotary wet-spinning biofabrication and electro-mechanical stimulation for the in vitro production of functional myo-substitutes

3D bioprinting directly affects proteomic signature and myogenic maturation in muscle pericytes-derived human myo-substitute

EXTRACELLULAR BIOADDITIVES-ADJUVANTED INJECTABLE HYDROGEL SUPPORTS NEOANGIOGENESIS AND DAMPENS ADVERSE CARDIAC REMODELLING

ENGINEERING FUNCTIONAL MICROVASCULARIZED SKELETAL MUSCLE TISSUE EQUIVALENTS VIA MICROFLUIDIC-ASSISTED 3D WET-SPINNING AND MICROVASCULAR SEEDS

Improving the functionality of biofabricated myo-substitutes using a tailored electro-mechanical bioreactor

Microfluidic self-assembly of cell-laden microgels into clusters, chains and arrays: from organoids to vasculature networks engineering.

Harnessing microfluidic bioprinting to fabricate gradient-like porous 3D constructs via emulsion ink deposition

MICROFLUIDIC SPINNING OF HYDROGEL-BASED CORE-SHELL MICROFIBERS FOR THE FABRICATION OF MYOTENDINOUS TISSUE-LIKE CONSTRUCTS

Transition metal dichalcogenides (TMDC)-based nanozymes for biosensing and therapeutic applications

Oxygenation therapies for improved wound healing: current trends and technologies

Analysis of the available funds supporting marine activities in some key European Mediterranean countries

Hydrogel-based fiber biofabrication techniques for skeletal muscle tissue engineering

4D printing in biomedical applications: emerging trends and technologies

Mimicking the nature with biofabrication

From adaptive self-assembly to avalanching instabilities in driven soft-granular matter.

Oxygen releasing materials: towards addressing the hypoxia-related issues in tissue engineering

Nanotechnology‐Assisted RNA Delivery: From Nucleic Acid Therapeutics to COVID‐19 Vaccines

Extrusion 3D printing with Pectin-based ink formulations: Recent trends in tissue engineering and food manufacturing

Recent advances in bioprinting technologies for engineering cardiac tissue

Recent advances in bioprinting technologies for engineering different cartilage-based tissues

Tumor extracellular matrix stiffness promptly modulates the phenotype and gene expression of infiltrating T lymphocytes

Alginate-based tissue-specific bioinks for multi-material 3D-bioprinting of pancreatic islets and blood vessels: A step towards vascularized pancreas grafts

Biofabricating murine and human myo‐substitutes for rapid volumetric muscle loss restoration

Recent advances in chemically defined and tunable hydrogel platforms for organoid culture

In vivo organized neovascularization induced by 3D bioprinted endothelial-derived extracellular vesicles

3D Printing of Biphasic Inks: Beyond Single-Scale Architectural Control

Tackling Current Biomedical Challenges with Frontier Biofabrication and Organ-on-a-Chip Technologies

Recent advances in tissue engineering and anticancer modalities with photosynthetic microorganisms as potent oxygen generators

Nanotechnology‐Assisted RNA Delivery: From Nucleic Acid Therapeutics to COVID‐19 Vaccines (Small Methods 9/2021)

Skeletal muscle-derived Human Mesenchymal Stem Cells: influence of different culture conditions on proliferative and myogenic capabilities

Extrusion and Microfluidic‐Based Bioprinting to Fabricate Biomimetic Tissues and Organs

Photocurable Biopolymers for Coaxial Bioprinting

Phalanx Reconstruction for Extremity Functional Recovery

Co-axial wet-spinning in 3D bioprinting: state of the art and future perspective of microfluidic integration

3D bioprinted hydrogel model incorporating β -tricalcium phosphate for calcified cartilage tissue engineering

3D‐Printing of Functionally Graded Porous Materials Using On‐Demand Reconfigurable Microfluidics

3D bioprinting in skeletal muscle tissue engineering

Engineering human-scale Artificial bone grafts for treating critical-size bone defects

3D bioprinting of hydrogel constructs with cell and material gradients for the regeneration of full-thickness chondral defect using a microfluidic printing head

3D tissue modelling of skeletal muscle tissue

Tendon tissue engineering: effects of mechanical and biochemical stimulation on stem cell alignment on cell‐laden hydrogel yarns

Aligned Cell‐Laden Yarns: Tendon Tissue Engineering: Effects of Mechanical and Biochemical Stimulation on Stem Cell Alignment on Cell‐Laden Hydrogel Yarns (Adv. Healthcare …